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Silencing Long non-Coding RNA NEAT1 Attenuates Rheumatoid Arthritis via the MAPK/ERK Signalling Pathway by Downregulating microRNA-129 and microRNA-204

These results might provide a more detailed understanding of how the T cell metabolism and thus function and insight into how T cells works in TCMR

Shafira Ninditya, MD, as the corresponding authors research assistant who provided editorial assistance in the preparation of this article

An important next step will be to establish robust biomarkersmolecular, lipidomic and functionalthat predict response to CoQ 10 -axis perturbation alone or in combination with standard therapies

Immediate oxygen and glucose deprivation rapidly deplete ATP, disrupt the transmembrane ionic gradients, increase glutamate excitotoxicity, and overload mitochondrial with calcium