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GLP-1RAs as novel and promising drugs for T2DM, they could stimulate insulin secretion in a glucose-dependent manner, protect cell function, and suppress glucagon secretion (Sharma et al., 2018)
Ueland PM, Mansoor MA, Guttormsen AB, Mller F, Aukrust P, Refsum H, and Svardal AM (1996)
When blood glucose levels rise after eating, Ozempic stimulates the pancreas to release insulin in a glucose-dependent manner, meaning it only works when blood sugar is elevated
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Generally, the medications are recommended for people with a body mass index over 30 (the World Health Organizations definition of obesity) and those with a BMI of 27 or above and at least one obesity-related condition, such as diabetes, high blood pressure, or high cholesterol
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