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One of the most unique parts of GLP1s as a treatment is that they both treat the disease (e.g., obesity, diabetes) and can reduce obesity inducing behavior (unlike medication for hypertension)
Comparing progress with your own baseline is usually more meaningful than comparing yourself with another patient
This complication has been assessed with multiple systematic reviews with meta-analyses demonstrating that while there may be an increased risk of acute pancreatitis with the DPP-4 inhibitors, there is no clear association with GLP1-RAs 16
Stay tuned to my blog and Resiliency Radio podcast for updates on this evolving story
They change gastrointestinal function in ways that matter for perioperative safety
That third pathway is what separates retatrutide from everything else in the weight loss pipeline
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