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The most consistent problem was the near-total absence of human clinical trial data for the proposed routes of administration

The escalating prevalence, particularly during the last decades, has made NAFLD the second most common cause of liver transplantation in the United States [5]

Gudo ES, Silva-Barbosa SD, Linhares-Lacerda L, Ribeiro-Alves M, Real SC, Bou-Habib DC, Savino W

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doi: 10.1186/s12934-025-02682-4 94 ZarnowskiR.WestlerW