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However, the evidence is obtained that BPC 157 action initially affects expression of particular genes (i.e., Akt1, Grb2, Nos3, Pik3cd, Prkcg, Ptk2, and Src )
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Topical products also face stability challenges
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In the only human study, 11 of 12 patients receiving intra-articular BPC-157 injections reported significant knee pain improvement, with 7 maintaining relief over 6 months (Lee et al., 2021)
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