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Chronic social stress induces p16-mediated senescent cell accumulation in mice

Downstream IGF-1 Once GH is released, the liver converts most of it into IGF-1

Molecular hydrogen has recently emerged as a therapeutic medical gas with antioxidant, anti-inflammatory, and cytoprotective properties through selective free radical scavenging, activating antioxidant enzymes, reducing pro-inflammatory cytokines, and potentially modulating cell signaling

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Menati L, Khaleghinezhad K, Tadayon M, Siahpoosh A

Myostatin reduces Akt/TORC1/p70S6K signaling, inhibiting myoblast differentiation and myotube size