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The Alkylating Chemotherapeutic Temozolomide Induces Metabolic Stress in IDH1-Mutant [PMID: 28625978] Laboratory literature summary: The Alkylating Chemotherapeutic Temozolomide Induces Metabolic Stress in IDH1-Mutant Cancers and Potentiates NAD(+) Depletion-Mediated
In another hand, while most reports appear to implicate IGF-I as a potential mediator of pathological changes in the diabetic kidney[364, 365], IGF-I is also protective against oxidative stress and apoptosis induced by high levels of glucose in cultured mesangial cells
Maine Medical Center Institute for Research, Scarborough N Engl J Med 2026