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The first month is an introduction phase at a sub-therapeutic dose, so modest results are expected and normal
Although ALT is most reliable biomarker for detecting liver injury or hepatotoxicity, it is also prevalent in the heart, kidneys, skeletal muscle, and testes 85
careful dose titration with physician oversight minimizes discontinuation
It is important to monitor symptoms and avoid weight bearing into the wrist for 10-12 weeks
We handle titration, refills, and follow-up
Weeks 58: Response phase
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