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Despite its potential, evidence supporting GSHs long-term efficacy and safety is limited
doi:10.1046/j.1365-201x.1996.42256000.x
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(2) the specific CI inhibitor IACS-010759 was recently reported to promote neurotoxicity, making this an unattractive agent for combination therapy in CRC given the neurotoxicity long-recognized with oxaliplatin treatment 51
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