Nutrition 57 , 97108 (2019)
GLP-1 medications support weight loss by sending signals to the brain and body that help regulate metabolism and help patients feel full and satiated longer
The label cautions about possible reduced efficacy of oral contraceptives due to delayed gastric emptying
Essop T, Tran K, Purdy AC, et al
Compounded medications allow providers to adjust doses more precisely based on individual tolerance and response
In patients with DM2 the incretin response is diminished, but the insulinotropic effect of GLP-1 is conserved.28 Under normal conditions GLP-1 has a short half-life (approximately 2 min), as it is rapidly degraded by dipeptidylpeptidase 4, so GLP-1 analogues resistant to this enzyme have been developed for the treatment of DM2.29 arGLP-1: glucagon-like peptide 1 receptor agonist