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International guidelines recommend the use of GLP-1 analogues in T2DM patients with ASCVD or who have high cardiovascular risk [44, 45]
Medicare weight-loss drug copays vary, but the average out-of-pocket cost to obtain GLP-1s through Part D at the end of 2025 was $167 per month and climbing, according to a study by researchers at University of Pennsylvania
MA results showed that compared with the semaglutide, tirzepatide could produce significantly greater weight loss (MD = 4.23
A plan sponsor paying $50 per unit for a generic drug while the PBM reimburses the pharmacy $30 generates $20 per unit in spread revenue for the PBM
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