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Anti-Inflammatory and Antioxidant Effects: Investigate suppression of pro-inflammatory cytokines (e.g., IL-6, TNF-) and enhancement of superoxide dismutase (SOD) and other antioxidant pathways
The flow diagram of the literature search process is presented in online Supplementary Fig
Protection by protein binding of toxic adducts or transition metals (copper or iron) to albumin, transferrin, ferritin, ceruloplasmin or metallothionein, provides another rapid venue for detoxication (liver and systemic circulation)
In one late 1990s study, (6) a clinical trial was conducted on eight male test subjects with a concentration escalation design
A 2003 study by Staresinic et al
Cisplatin treatment resulted in a significant survival increase, as previously described 57 (Fig
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