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Perioperative management of oral glucose-lowering drugs in the patient with type 2 diabetes
Tirzepatide targets both GLP-1 and GIP receptors, supporting appetite control and insulin sensitivity
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A proof-of-concept study evaluating the phosphodiesterase 10A inhibitor PF-02545920 in the adjunctive treatment of suboptimally controlled symptoms of schizophrenia
The freeze-dried form is stable at room temperature for short periods during shipping (57 days at 1530C), but long-term storage requires freezer conditions to prevent moisture absorption and slow degradation
CRISPR/Cas9-mediated knockout and knockin was performed using the Neon Transfection System (Thermo Fisher Scientific): Synthetic CRISPR guide RNAs, ssODN Donors and recombinant Cas9 (IDT) were electroporated according to the manufacturers protocol and recommendations (1005 V, 35 ms, 2 pulses)
