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This controversy encompasses several critical aspects, including regulatory approval and off-label use, the balance of efficacy versus potential risks, cost and accessibility, equity in resource allocation, and the broader implications of medicalizing obesity

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By reducing insulin resistance through weight loss and direct metabolic effects, it decreases the demand placed on beta cells

It is available in two forms: insoluble and soluble

40 Most cases in the literature demonstrate improvement of psoriasis after the initiation of GLP-1RAs, but one report described a patient with an exacerbation of psoriatic lesions after the initiation of liraglutide