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Ipamorelin hits the GHRP receptor and says "release GH now." CJC-1295 (no DAC) hits the GHRH receptor and says "amplify that release." When dosed together: CJC-1295 primes the pituitary and increases the available pool of GH Ipamorelin triggers the acute release of that pool The combined pulse is substantially larger than either compound generates alone research suggests synergistic effects in the range of 210x depending on baseline GH status and dosing This works because the two compounds bind to completely separate receptors
Varghese, J
Energy metabolism in mammalian sperm motility
J Biol Chem 193:265275
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~ AlphaMD Many people associate nicotine primarily with smoking and tobacco use, but with the growing popularity of nicotine gum, patches, and other alternatives, questions arise about how nicotine itself affects the body
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