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Determine the appropriate medication hold window based on type
Concerns about important biases, such as selection bias, serious confounding by indication, detection bias, or reverse causality, limit the interpretation of some previous observational studies quantifying dementia risk associated with GLP1 receptor agonists (Supplementary Table 14 for further details)
Of these patients, a large proportion initiating oral semaglutide (36.1%) had no prior evidence of GLP-1-therapy use, suggesting that early adoption included a substantial proportion of patients new to using GLP-1 medications
Some clinics have started using this as a core part of multi-modal hair protocols
Nauck et al., 2020): Compounds based on the lizard-derived exendin-4 peptide and compounds based on the human GLP-1 peptide
Their metabolism slowed because they lost muscle, and when the appetite suppression went away, the math no longer worked in their favor
