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143 Powered by ATP hydrolysis, they actively extrude cytotoxic agents from tumor cells, thereby reducing intracellular drug concentrations below therapeutic thresholds

However, overtraining without adequate rest can have the opposite effect, so balance is key

This makes it an ideal choice for animals experiencing Vitamin B12 deficiencies or those with increased metabolic demands, such as during periods of growth, pregnancy, lactation, or high-performance activities

Pharmaceutics 16 , 561572 (2019)

This knowledge led to the hypothesis that increased levels of Gsto2 in iSPNs can disrupt AA homeostasis, leading to changes in TH protein levels and increased DA synthesis in striatal projecting mDA neurons that potentially express no or low TH in the adult brain

This is unfortunate, as studies have found that poor sleep is itself a form of stress and can lead to decreases in glutathione levels and oxidative damage