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2021 Nov 29;134(1):149
Table 12: Study of Different Times of Once Daily Insulin Glargine Dosing in Type 1 (Study H) and Type 2 (Study I) Diabetes Mellitus Progression Of Retinopathy Evaluation In Adults With Diabetes Type 1 And Diabetes Type 2 Insulin glargine was compared to NPH insulin in a 5-year randomized clinical study that evaluated the progression of retinopathy as assessed with fundus photography using a grading protocol derived from the Early Treatment Diabetic Retinopathy Scale (ETDRS)
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Video 1 (download MOV Different hydration of polar networks within the GLP-1R transmembrane (TM) domain
Patient stories from trials often mention improvements in quality of life being able to move more easily, reduced joint pain, better sleep (especially if sleep apnea improves), and of course the emotional boost of seeing significant weight change
If retatrutide prevents type 2 diabetes ($9,600 per year average treatment cost), cardiovascular disease ($20,000+ per year), or joint replacement surgery ($50,000 one-time cost), it pays for itself within 1-2 years even at full price
