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For patients with a naturally small cup-to-disc ratio, a structural characteristic of the optic nerve, the risk appears higher
10.1016/j.atherosclerosis.2013.10.025
Sanchez-Delgado, G., et al
Meanwhile, new competitive threats continued to surface: in 2025, Lilly unveiled impressive results for an oral GLP-1 pill (orforglipron) that in trials matched injectable Ozempic's efficacy, news that instantly added ~$100 billion to Lilly's market cap
That, along with the low 100mg silymarin dosage, should tip you off to the fact that milk thistle plays only a supporting role in the formulation
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