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Patients beginning semaglutide should establish stable medication tolerance (usually 4-6 weeks at a consistent dose) before implementing IF beyond 12-14 hour fasts
This finding suggests they have used the drug recently
FDA approval is not expected before late 2027
Additionally, GLP-1 RAs were effective in reducing alcohol and substance use and binge eating behaviors
This dual mechanism may contribute to greater reductions in HbA1c and body weight in clinical trials
An examination of pharmacy- and medical-claims data from 2021 for 4,066 nondiabetic GLP-1 users with obesity found 53.7 percent discontinued use within 180 days, and 67.7 percent stopped within a year
