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Of these, 63 articles were excluded based on various reasons, as demonstrated in Supplementary Material 2

111:352-358 (1992) Jeon GB, Lee HJ, Park JP, Park K, Choi CH, Kim SK

PlexusDx providers maintain contact with patients throughout treatment, adjust doses based on tolerance and results, and screen for side effects like nausea, injection-site reactions, or gastrointestinal changes

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HGH (Somatropin): FDA-approved for specific indications: pediatric growth hormone deficiency, adult GHD, Turner syndrome, HIV/AIDS-related wasting, short bowel syndrome Prescription-only medication requiring physician monitoring Illegal to distribute for off-label purposes including anti-aging (per the 1990 Anabolic Steroids Control Act amendments) Brand names include Genotropin, Norditropin, Humatrope, Saizen CJC-1295 and Ipamorelin: Neither is FDA-approved for any therapeutic indication Available as research compounds for laboratory use only (RUO Research Use Only) Not scheduled substances, but not approved for human therapeutic use Ipamorelin has undergone Phase I/II clinical trials (Johansen et al., 1999) but development did not progress to approval For a deeper look at Ipamorelin's regulatory history, see our Ipamorelin FDA approval status guide

Social media comparisons can be misleading and discouraging, as everyones progress timeline is different and often slower than online expectations