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Side Effects: Common Side Effects: Nausea , vomiting , diarrhea , abdominal pain , and bloating are common , especially at higher doses
Reducing absorption Makes it so your body is less able to process certain nutrients such as fat, so your body metabolizes fewer calories
doi: 10.1016/j.diabres.2024.111806
The 30-Second Verdict I pulled the head-to-head Phase 3 data, the SURMOUNT-5 NEJM paper, and the December 2025 TRIUMPH-4 topline readout side by side
Some patients even benefit from PlexusDx's GLP-Squared dual-compound option, which combines both mechanisms in a single injection for maximum flexibility
Your eligibility for a GLP-1 agonist is based on your BMI as well as your medical history such as if you have type 2 diabetes and risk factors
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