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Week 46 is the most critical monitoring window : As semaglutide doses escalate and appetite suppression intensifies, early lean mass loss can establish a downward trajectory that compounds over months

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First, the growing recognition that BMI is a flawed metric is driving conversations about alternative eligibility criteria

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That acknowledged, a potential criticism of the present analysis is that only one treatment pathway was tested, with initial therapies discontinued when HbA1c exceeded 7.5%treatment algorithms that added basal insulin alongside oral semaglutide, empagliflozin or dulaglutide were not explored

Manage your diabetes monitor glucose levels regularly and go to a doctor if you are prone to hypoglycemia.