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The National Academy of Sciences recommends approximately 91 ounces (2.7 liters) of total water daily for women and 125 ounces (3.7 liters) for men from all beverages and foods, though individual needs vary based on activity level, climate, and health status

Tirapazamine: a hypoxia-activated topoisomerase II poison

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It exerts antimicrobial effects in the immune system by rapidly oxidizing bacterial proteins to combat invading microorganisms

However, it may have some protective effects against skin aging and may help reduce freckles and age spots to some extent (1)

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