This happens when too much fat builds up in the liver
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For instance, someone who doesnt meet the strict BMI threshold but shows clear signs of insulin resistance on a HOMA-IR score might still benefit from low-dose GLP-1 therapy
Wolf, and M.C Petrie, for the STEP-HFpEF Trial Committees and Investigators* Relevant literature The STEP-HFpEF group has previously published the study design and baseline patient characteristics of this RCT 2 Relevant RCTs below: Relevant Guidelines 2022 AHA/ACC/HFSA Guidelines of the Management of Heart Failure: A Report of the ACC/AHA Joint Committee on Clinical Practice Guidelines
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