You can't build upon or trust data that comes from a compromised foundation
In summary, the key interactions to consider are pyridoxines reduction of levodopa and anticonvulsant efficacy, niacinamides additive effects on blood pressure, blood sugar, and gout management, and the potential need for B-vitamin repletion in patients on certain medications (diuretics, isoniazid, etc.)
Journal of Clinical Endocrinology & Metabolism
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The methods used are necessary for validation in tissue engineered constructs that may over estimate strain transfer compared to native tissue 5
For risks and side effects, read the package leaflet and consult your doctor or pharmacist