10.1038/s41398-017-0031-4 494 YangJ.-Z.ZhangK.-K.LiuY.LiX.-W.ChenL.-J.LiuJ.-L.et al
This dual antioxidant mechanism explains GHK-Cu's protective effects in inflammatory conditions and its ability to enhance cellular survival under stress conditions
biological function 2016 Distribution of glutathione and glutathione-related enzyme systems in mitochondria and cytosol of cultured cerebellar astrocytes and granule cells.1995 One gene two localization in mitochondria and cytosol Tom70 enhances mitochondrial preprotein import efficiency by binding to internal targeting sequences 2018 Enzymes Cell signaling and Ligand transport Structural proteins REGULATION DIAGNOSTIC USE Targeting Nrf2 to Suppress Ferroptosis and Mitochondrial Dysfunction in Neurodegeneration 2018 The plant mitochondrial import machinery
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The interaction of genetics, autoimmunity, oxidative stress and other pathogenetic mechanisms results in damage, dysfunction and apoptosis of MCs, and melanin production is blocked, ultimately leading to vitiligo