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Healthcare providers should rely on this official safety information rather than anecdotal reports when counseling patients about neurological risks
(2015) 10(5):e0127111
GLP-1 refers to a class of medications GLP-1 receptor agonists such as semaglutide, liraglutide, and dulaglutide alongside the GIP/GLP-1 dual agonist tirzepatide, which adds a second incretin pathway
Function The GLP-1 receptor (GLP-1R) is a seven-segmented transmembrane protein with an extracellular amino terminus and an intracellular carboxyl terminus
Moreover, the modified GLP-1 RAs, which are designed to activate the GLP-1 receptor more effectively, have stronger neuroprotective efficacy than GLP-1 RAs used in clinical practice
doi: 10.1002/glia.23962 328 SomjenG
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