Side Effects and Risks Possible side effects that have been associated with the administration of glutathione are: Allergic reactions Bronchial constriction that may lead to trouble in breathing Bloating Abdominal cramps Itchiness Fatigue Thyroid dysfunction Kidney dysfunction According to many clinical studies, side effects are very closely related to the dose of glutathione in supplements administration
If considering nasal administration, recognize that absorption and dosing precision may differ from injection
Arch Biochem Biophys 459:295300, PMID: 17169322 Lou H, Kaplowitz N (2007) Glutathione depletion down-regulates tumor necrosis factor alpha-induced NF-kappaB activity via IkappaB kinase-dependent and -independent mechanisms
Mechanisms underlying cardiac protection include enhanced coronary angiogenesis, antioxidant effects reducing oxidative damage, anti-inflammatory modulation limiting inflammatory cell infiltration, and direct cardiomyocyte protection
As each person's reaction to glutathione can differ markedly, having an informed discussion with your healthcare provider about the potential benefits and risks is key to tailoring a treatment plan that aligns with your skin whitening aspirations
Br J Cancer 66:589593