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Elevated insulin drives de novo lipogenesis (fat synthesis from carbohydrates), so reducing insulin through improved receptor sensitivity indirectly reduces hepatic fat accumulation
Discontinuation rates were 8.7 percent at the 12 mg dose and 9.7 percent at 36 mg, compared with 4.5 percent and 4.9 percent for oral semaglutide at 7 mg and 14 mg
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The specific role and related mechanisms of GLP-1RAs in the bone metabolism of patients with different types of osteoporosis need to be further explored and clarified
STEP UP, 72-week study of adults with obesity using Wegovy (semaglutide 7.2mg)
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