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Based on clinical analysis, tirzepatide serves as the base drug for several brands
Beyond the M2-polarization function, GLP-1R activation also supports macrophage migration, which may be mediated by its regulation of macrophage polarization and the effects of IL-6 [93, 94]
These individuals should not receive these specific GLP-1 medications due to the theoretical risk suggested by animal studies, even though human causality remains unproven
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