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Alterations of the thalamo-cortical system in rats prenatally exposed to ethanol are prevented by concurrent administration of acetyl-L-carnitine Brain Res 1995

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2 Weight loss pharmacotherapies 2.1 GLP-1R and GIPR agonism reduce body weight in patients with obesity Early GLP-1R agonists were approved to treat T2D (13, 15, 16), but the potential weight lowering efficacy for this class of molecules first seen in rodents was not confirmed in humans until clinical trials with the first long-acting GLP-1 analogue, liraglutide (12)

Therefore, both the increase in the survival of transformed B cells and the increase in antigen presentation generated by the increase in HLA-II expression by estradiol may favor an increase in the presentation of both self and foreign antigens during an infectious process, and those abnormal plasma cells producing autoantibodies survive longer, which consequently increases the probability of women developing autoimmune diseases or even cancer [171]

Pharm Biol 54(7):11981208

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