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Some individuals experience severe reactions, including gastrointestinal issues, low blood sugar, and even infections from improperly compounded injections
Severe adverse effects (requiring study discontinuation) were reported in 6.7% of cases and 3.0% of controls
A 15% CV cut-off was used
Starting with CJC-1295/Ipamorelin, transitioning to sermorelin for maintenance: A patient uses CJC/Ipa to achieve target body composition and IGF-1 levels, then steps down to sermorelin for long-term maintenance with a lighter protocol
New insights on the cardiovascular effects of IGF-1 [PMID: 36843588] Laboratory literature summary: New insights on the cardiovascular effects of IGF-1
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