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Compounded versus brand-name semaglutide: does onset differ
Participants who received semaglutide had greater reductions in the number of heavy drinking days (41% fewer, on average) compared to those receiving placebo (26%.) The amount of alcohol consumed over the prior 30 days dropped by over 70% in the semaglutide group (from 78 ounces of 100% alcohol at baselinethe equivalent of 130 shots of 80-proof spirits over 30 daysto 23 ounces, or about 39 shots)
Tirzepatide was also associated with dose-dependent positive changes in lipids, with a reduction in triglycerides and increases in HDL cholesterol
At Charleston Healthspan Institute, we take a comprehensive and structured approach to combining supplements with bioidentical hormone therapy
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Whats more, a recent retrospective, multicenter cohort study denied higher occurrence of nonarteritic anterior ischemic optic neuropathy (NAION) in GLP-1RAs users and suggested that its potential benefits for blood glucose control and cardiovascular health likely outweigh its risks (Chou et al., 2025), despite that a few research have reported association between semaglutide prescription and a higher risk of NAION(61)
