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Regulation by Acetylation and Methylation Acetylation of -KG dehydrogenase and other TCA cycle enzymes can influence the activity and efficiency of the cycle
J.JohnsonD
Abstract Alterations in excitatory neurotransmitters, involving the glutamate (Glu) and glutamine (Gln) cycle, as well as inhibitory neurotransmission, GABA, are implicated in the pathophysiology of autism spectrum disorder (ASD)
Rather than forcing these processes pharmacologically, the energetic remedy acts as a template or tuning fork
Upstream molecular targets, such as Nrf2, Sirt3, and PPAR-, are responsible for the curcumin-enhanced GSH system [184,185,186]
& Camaschella, C
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