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The binding affinity of GLP-1RAs to the GLP-1 receptor on rat insulinoma cells (Fuxiang Biotechnology, Shanghai, China) was measured using a human GLP1 (7-36) ELISA kit (Abcam, Waltham, MA, USA)

Representative domains include: Gastrointestinal and hepatic models: Protection against ulcers, leaky gut, IBSlike symptoms, Crohntype inflammation, and toxic liver injury (e.g., CCl4, NSAID, and alcohol models), with improved mucosal healing and barrier integrity

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Under the brand name Mounjaro, it is approved as an adjunct to diet and exercise to improve glycemic control in adults with type 2 diabetes mellitus

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10.1016/j.envres.2024.120250 Environ