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Gastrointestinal side effects (nausea, vomiting, diarrhea) are the most common reason people discontinue treatment
Adipose tissue functions as an endocrine organ, producing estrogen through the aromatization of androgens
The self-pay segment includes patients willing to bear substantial out-of-pocket costs averaging USD 1000 per month to access treatment not covered by their insurance plans
"Characterization of glucagon-like peptide-1 receptor beta-arrestin 2 interaction: a high-affinity receptor phenotype"
Mechanism appears multifactorial: upregulation of nerve growth factor (NGF), brain-derived neurotrophic factor (BDNF), and synaptic plasticity proteins like synaptophysin
