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Not having enough folate during fetal development causes abnormalities of the brain, says Dr Edward Quadros, a professor in the department of medicine at SUNY Downstate who specializes in folate absorption

Vitamin B12 plays a key role in regenerating nerve cells and restoring proper function

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J Pediatr Gastroenterol Nutr 50:132139 Varga C, Laszlo F, Fritz P, Cavicchi M, Lamarque D, Horvath K, Posa A, Berko A, Whittle BJ (2007) Modulation by heme and zinc protoporphyrin of colonic heme oxygenase-1 and experimental inflammatory bowel disease in the rat

The extracellular N-terminus contains key regions involved in ligand recognition and binding