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Exp Gerontol (2010) 45:2027
Fatigue is one of the first signs of B12 deficiency
PT/INR) should be monitored frequently, especially in the first two weeks
For others, a nighttime dose supports the body's natural repair cycles
On GLP-1 medications, you're fighting three dehydration mechanisms simultaneously: Reduced thirst signaling (central appetite suppression affects thirst centers) Reduced fluid intake with meals (nausea makes drinking unpleasant) Ongoing fluid loss from glycogen metabolism during weight loss The result is chronic mild dehydration in a substantial portion of patients during titration
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