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[1] Because intrinsic-factor-dependent uptake in the distal ileum can be absent in conditions such as autoimmune gastritis, pancreatic insufficiency, or bariatric surgery, the intramuscular or subcutaneous route bypasses gastrointestinal barriers and reliably restores serum concentrations
However, on average patients will see a response from the vitamin B12 injections around 48 to 72 hours after, with brisk production of new red blood cells
the dose per injection remains 2.8 mg
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