Clinical trials show that discontinuing GLP-1 therapy leads to weight regain in approximately 70% of patients within one year, underscoring why these medications function best as long-term treatment rather than temporary interventions
Post-protocol (2-4 weeks after finishing): Full retest
Administration Injection type: Intramuscular (IM) or subcutaneous IM injection sites: Deltoid (upper arm), gluteus (buttock), or vastus lateralis (outer thigh) Subcutaneous sites: Abdomen, outer thigh, or back of upper arm Needle gauge: 25-27 gauge for IM, insulin syringe for subcutaneous Timing: Morning or early afternoon is preferred, as the energy boost may interfere with sleep if taken late in the day
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It arrives in lyophilized form because freeze-drying removes moisture, which dramatically extends stability lyophilized powder can remain stable for up to 3 years when stored properly
It's a significant side effect that deserves serious attention as this medication approaches approval