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Lancet Diabetes endocrinol (2020) 8(5):37791

Specifically, CLP-induced systemic inflammation may activate microglia to secrete pro-inflammatory mediators, which suppress the Nrf2/HO-1/GPX4 redox axis, triggering mitochondrial dysfunction and oxidative stress

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SELECT (cardiovascular outcomes in people with prior CVD and overweight/obesity): Semaglutide reduced major CV events by 20%

International Immunopharmacology, 75 , Article 105801