Tirzepatide is a dual agonist at GLP-1 and glucose-dependent insulinotropic polypeptide (GIP) receptors and produces enhanced glycemic control and greater weight loss compared to many GLP-1 RAs [34]
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When it comes to weight loss, providers and patients argue that GLP-1 medications are not a one-for-one swap and that volatile insurance coverage contradicts the science and experience of people managing obesity as a chronic disease
Most employer plans allow coverage for GLP1 drugs when prescribed for diabetes, but only a few employers cover GLP1s for weight loss, often with restrictions like body mass index (BMI) thresholds or lifestyle program participation
Its high sodium content gives it a distinctly salty flavor, which takes some getting used to