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Kidney disease or impaired kidney function

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If you are starting tirzepatide for the first time and your pharmacy sends a 40 mg/mL vial, ask them to reconsider

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Beyond weight loss and increasing feelings of satiety and fullness, semaglutide also offers the following health benefits to the body: While effective on its own, semaglutide yields optimal results when combined with lifestyle changes, like following a healthy diet and staying active with regular exercise for an overall enhanced well-being

For most people, those changes are temporary, manageable, and well worth it in the long run