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doi: 10.3389/fendo.2023.1194089 Received 26 March 2023 Accepted 30 June 2023 Published 27 July 2023 Volume 14 - 2023 Edited by Changyin Zhou, Guangdong Second Provincial General Hospital, China Reviewed by Xianyi Cai, Hefeng Central Hospital, China
Bring an insulated bag, if needed, and keep the medication with you in its original carton, preferably in a carry-on bag
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Genetic testing reveals predispositions in metabolic pathways but does not predict exact medication response or side effect tolerance
Statistical testing and construction of graphs were done in GraphPad Prism version 10.1.2 (GraphPad Software, La Jolla, CA)
Specific Mechanistic Effects Laboratory studies have documented cagrilintide-associated effects, including: Satiety-promoting signaling linked to reduced food intake Delayed gastric emptying , reflected by slowed gastric transit Reduced post-prandial glucagon secretion Enhanced regulation of energy balance Modulation of hypothalamic appetite centers and feeding-behavior circuits These effects arise from activation of the amylin and calcitonin receptors in appetite-regulating brain regions and peripheral metabolic tissues
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