In Summary GLP1 medications do more than reduce appetitethey reshape gut microbiota
In the JAMA paper: expression of the GLP-1 receptor in the human optic nerve and GLP-1 RAinduced enhanced sympathetic nervous system activity might influence optic nerve head perfusion. =Rapid lowering of blood glucose (and rapid change in metabolic state) in persons with pre-existing retinopathy may worsen ocular microvascular conditions (though this is more established with insulin rather than semaglutide specifically)
What is oxidative stress
That is the highest weight loss ever recorded for any drug (Lilly Press Release, Dec 2025)
These catabolic reactions include the suite of cellular processes that breakdown carbohydrates, fats, proteins, and alcohol, so they can be turned into cellular energy
In this installment, were highlighting safety updates concerning these drugs: Byetta, Bydureon BCISE, Mounjaro, Saxenda, Soliqua 100/33, Trulicity, Victoza, and Xultophy 100/3.6