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Why it was included in the FDA ban The FDA cites risk for immunogenicity, peptide-related impurities, and limited safety-related information as reasons for the BPC-157 ban
Topical application is the preferred route for cosmetic-adjacent skin research because it delivers the peptide directly to the target tissue while avoiding systemic exposure
Glucuronidation: UGTs catalyze an SN2 nucleophilic substitution where the substrate's nucleophilic functional group (OH, NH2, SH, COOH) attacks the C1 carbon of glucuronic acid in UDPGA, displacing UDP
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