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all citations on this page refer exclusively to pre-clinical animal studies and peer-reviewed mechanistic research and do not constitute a claim of safety or therapeutic efficacy in humans
People who are pregnant, breastfeeding, or managing active cancer or other serious conditions should not start it without specialist guidance
side-effect frequency rises
Starchenka et al
10.1074/jbc.M803623200 95 rdD.rdT.BieneT.rdT
Originally FDA-approved as an acne treatment in 1971, tretinoin was found to also improve signs of photoaging, such as wrinkles, brown spots and skin laxity
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