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However, this does not explain the fact that, in the ER, the ratio of reduced to oxidized glutathione ([GSH]:[GSSG]) is optimal for disulphidebond formation (Lyles & Gilbert, 1991)
For example, the landmark Penn State study demonstrated that natural killer (NK) cell cytotoxicitya key measure of the immune system's ability to clear virally infected cellsincreased more than twofold in subjects receiving high-dose glutathione
(PubMed) Jiang Q, Christen S, Shigenaga MK, Ames BN
Maybe it was longer than that
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