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While reductions in ALT often correlate with decreased hepatic inflammation and fat content, it's important to recognise that these are surrogate markers and do not definitively confirm histological improvement

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When BCBS covers Zepbound, typical PA requirements include: BMI 30 or 27 with a comorbidity (hypertension, type 2 diabetes, high cholesterol, or OSA), 6 months of documented lifestyle modification (diet and exercise program), and sometimes step therapy requiring trial of other weight loss medications first

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Enhances Circulation & Performance: Improved blood flow, supports endurance, workout performance, and recovery

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Blood 138 , 11821193 (2021)

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That glucose-dependent action is why GLP-1s rarely cause hypoglycemia unless combined with insulin or sulfonylureas

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